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  • Diphenhydramine is given by mouth or as an injection and is used on and off label to treat allergic reactions, motion sickness, and to induce sedation. Side effects include sleepiness, and less commonly dry mouth and gastrointestinal upset.

  • Doxepin is given by mouth and is used off label to treat psychogenic dermatoses such as excessive grooming and psychogenic alopecia. Give as directed. The most common side effect is sleepiness. Do not use in pets that are allergic to it or other tricyclic antidepressants, in pets currently using an MAOI or flea/tick collar, or in pets undergoing skin allergy testing within two weeks. If a negative reaction occurs, please call your veterinary office.

  • Doxycycline is an antibiotic given by mouth in the form of a tablet, capsule, or liquid, used off label to treat certain infections. Common side effects include stomach upset, sun sensitivity, and increases in liver enzymes. Serious side effects include liver failure, seizures, and trouble swallowing. Do not use in pregnant pets and use cautiously in pets with liver disease or in young pets. If a negative reaction occurs, please call your veterinary office.

  • Enalapril is used on and off label and is given by mouth or injection to treat heart failure, high blood pressure, chronic kidney disease, or proteinuria. Common side effects include loss of appetite, vomiting, diarrhea, and tiredness. Do not use in pets that are allergic to it, have an acute kidney injury, or have certain heart conditions.

  • Enrofloxacin is an antibiotic given by mouth or in the muscle commonly used to treat bacterial infections in cats, dogs, and off label in small mammals, birds, and reptiles. Common side effects include vomiting, diarrhea, and lack of appetite. It should not be used in growing or dehydrated pets, or in cats with kidney disease. Use cautiously in pets with seizures, liver, or kidney disease. If a negative reaction occurs, please call your veterinary office.

  • Erythromycin is given by mouth or injection and is used off label to treat bacterial infections and gastrointestinal motility problems in many animal species. Common side effects include diarrhea, lack of appetite, and vomiting. Do not use in pets that are allergic to it, have liver disease or dysfunction, or in pets such as rabbits, gerbils, guinea pigs, or hamsters. If a negative reaction occurs, please call your veterinary office.

  • Erythromycin ophthalmic is an antimicrobial medication used to treat certain types of eye infections. It may be used “off label” or “extra label” to treat other eye conditions. Erythromycin ophthalmic comes in ointment form. Caution when using this medication in pocket pets as fatal diarrhea may occur if ingested orally.

  • Fluoxetine is given by mouth and is used on and off label to treat various behavioral conditions. Common side effects include sleepiness and decreased appetite. If a negative reaction occurs, call your veterinary office.

  • Furosemide is given by mouth or injection and is used on and off label to treat many conditions, including congestive heart failure and fluid retention. Common side effects include increased urination, diarrhea, or constipation. Do not use in pets that are allergic to it or in those that are unable to make urine.

  • There are multiple methods of inheritance that determine which characteristics (or phenotypes) are displayed by the offspring, including autosomal dominant, autosomal recessive, and sex-linked inheritance. There are also many polygenic traits (i.e., associated with multiple genes) as well as environmental factors that make it much more complicated to predict disease or the likelihood of passing disease onto offspring.